Skip to main content
Free research Free research Free target review with research home and workspace preview
Quick search ChEMBL 36
Loading Target Snapshot...
Querying ChEMBL database. This may take a few seconds.
Target Snapshot

CHEMBL2871 Target Snapshot

Cholecystokinin receptor type A · SINGLE PROTEIN · Rattus norvegicus

1,371Compounds
155Assays
5Approved Drugs
1,549.0Activities
Free Research Context

Research home keeps recent targets

This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.

Navigation

Switch target

Move to another high-traffic target or paste a specific ChEMBL target ID.

Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt P30551. Use UniProt P30551 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P30551 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Cholecystokinin receptor type A as ChEMBL target CHEMBL2871, mapped to UniProt P30551. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Cholecystokinin receptor type A
SINGLE PROTEIN · Rattus norvegicus
As of 2026-09-13
ChEMBL target ID
CHEMBL2871
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
P30551
Cholecystokinin receptor type A
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Cholecystokinin receptor type A is the right protein anchor across sources, using UniProt P30551 as the stable mapping.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelCholecystokinin receptor type A
UniProt AccessionP30551
Component TypeProtein
Sequence Length444 aa

Cholecystokinin receptor type A

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Cholecystokinin receptor type A, mapped to UniProt P30551. Sequence length is 444 aa.

Mapped IDP30551
Review nameCholecystokinin receptor type A
OrganismRattus norvegicus
Clinical Profile

Clinical Phase Distribution

5
Approved
12
Phase II
2
Phase I
Assay Mix

Activity Type Distribution

IC501,344.0
KI197.0
EC508.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL3143672 10.7 Ki 0.02 Preclinical
CHEMBL76248 10.52 Ki 0.03 Preclinical
CHEMBL1161142 10.52 Ki 0.03 Preclinical
CHEMBL423907 10.52 Ki 0.03 Preclinical
CHEMBL3142366 10.3 Ki 0.05 Preclinical
CHEMBL323521 10.3 IC50 0.05 Preclinical
CHEMBL411079 10.3 IC50 0.05 Preclinical
CHEMBL137280 10.15 Ki 0.07 Preclinical
CHEMBL9506 10.1 IC50 0.07943 Clinical
CHEMBL3350858 10.05 IC50 0.09 Preclinical
Distribution

pChEMBL Value Distribution

137
5.0
246
5.5
260
6.0
179
6.5
111
7.0
99
7.5
75
8.0
61
8.5
39
9.0
12
9.5
pChEMBL
Approved Drugs

Approved Drugs

SINCALIDE
CHEMBL1121
Approved 1976
PENTAGASTRIN
CHEMBL1328
Approved 1974
Assay Landscape

Assay Landscape

155
Total Assays
1,166
Tested Compounds
2
Assay Types
Binding — 150 assays, 1,166 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 73 605 6.6
assay format 46 394 6.4
cell membrane format 17 150 7.0
tissue-based format 8 7 5.3
cell-based format 5 10 7.2
organism-based format 1 0
Functional — 5 assays, 6 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 2 1 6.8
tissue-based format 2 0
cell-based format 1 5 6.5

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine