Histone deacetylase 6 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt Q9Z2V5. Use UniProt Q9Z2V5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9Z2V5 as the stable identity anchor, then attach disease evidence before program review.
Protein deacetylase HDAC6
Review this target as Histone deacetylase 6, mapped to UniProt Q9Z2V5. ChEMBL maps the protein component as Protein deacetylase HDAC6. Sequence length is 1149 aa.
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This review treats Histone deacetylase 6 as ChEMBL target CHEMBL2878, mapped to UniProt Q9Z2V5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Histone deacetylase 6 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q9Z2V5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Protein deacetylase HDAC6 |
| UniProt Accession | Q9Z2V5 |
| Component Type | Protein |
| Sequence Length | 1149 aa |
Protein deacetylase HDAC6
Review this target as Histone deacetylase 6, mapped to UniProt Q9Z2V5. ChEMBL maps the protein component as Protein deacetylase HDAC6. Sequence length is 1149 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL343448 | 9.2 | IC50 | 0.625 | Approved |
| CHEMBL99 | 8.55 | IC50 | 2.8 | Preclinical |
| CHEMBL2018302 | 8.36 | IC50 | 4.4 | Preclinical |
| CHEMBL394261 | 8.06 | IC50 | 8.8 | Preclinical |
| CHEMBL4636622 | 8.01 | IC50 | 9.7 | Preclinical |
| CHEMBL390991 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL1790587 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL2158745 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL379049 | 7.64 | IC50 | 23.0 | Preclinical |
| CHEMBL241555 | 7.62 | IC50 | 24.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 57 | 70 | 6.9 |
| single protein format | 7 | 10 | 6.6 |
| assay format | 3 | 0 | — |
| tissue-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 20 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 9 | 6.2 |