Cytochrome P450 11B1, mitochondrial · SINGLE PROTEIN · Bos taurus
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As of 2026-09-14Protein identity stays anchored to UniProt P15150. Use UniProt P15150 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P15150 as the stable identity anchor, then attach disease evidence before program review.
Cytochrome P450 11B1, mitochondrial
Review this target as Cytochrome P450 11B1, mitochondrial, mapped to UniProt P15150. Sequence length is 503 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cytochrome P450 11B1, mitochondrial as ChEMBL target CHEMBL2927, mapped to UniProt P15150. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cytochrome P450 11B1, mitochondrial |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P15150 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cytochrome P450 11B1, mitochondrial |
| UniProt Accession | P15150 |
| Component Type | Protein |
| Sequence Length | 503 aa |
Cytochrome P450 11B1, mitochondrial
Review this target as Cytochrome P450 11B1, mitochondrial, mapped to UniProt P15150. Sequence length is 503 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL328863 | 6.87 | IC50 | 135.0 | Preclinical |
| CHEMBL157101 | 6.82 | IC50 | 152.0 | Approved |
| CHEMBL319160 | 6.61 | IC50 | 247.0 | Preclinical |
| CHEMBL934 | 6.24 | Ki | 580.0 | Approved |
| CHEMBL440299 | 6.18 | IC50 | 660.0 | Preclinical |
| CHEMBL55378 | 5.82 | IC50 | 1530.0 | Preclinical |
| CHEMBL55746 | 5.79 | IC50 | 1630.0 | Preclinical |
| CHEMBL54171 | 5.58 | IC50 | 2640.0 | Preclinical |
| CHEMBL294460 | 5.48 | IC50 | 3300.0 | Preclinical |
| CHEMBL55819 | 5.32 | IC50 | 4780.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 10 | 4 | 6.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 14 | 5.3 |