Aldehyde dehydrogenase 1A1 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P51647. Use UniProt P51647 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P51647 as the stable identity anchor, then attach disease evidence before program review.
Aldehyde dehydrogenase 1A1
Review this target as Aldehyde dehydrogenase 1A1, mapped to UniProt P51647. Sequence length is 501 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Aldehyde dehydrogenase 1A1 as ChEMBL target CHEMBL2931, mapped to UniProt P51647. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Aldehyde dehydrogenase 1A1 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P51647 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Aldehyde dehydrogenase 1A1 |
| UniProt Accession | P51647 |
| Component Type | Protein |
| Sequence Length | 501 aa |
Aldehyde dehydrogenase 1A1
Review this target as Aldehyde dehydrogenase 1A1, mapped to UniProt P51647. Sequence length is 501 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL420451 | 5.78 | IC50 | 1660.0 | Preclinical |
| CHEMBL98797 | 5.6 | IC50 | 2500.0 | Preclinical |
| CHEMBL101776 | 4.68 | IC50 | 20900.0 | Preclinical |
| CHEMBL299785 | 4.62 | IC50 | 24000.0 | Preclinical |
| CHEMBL121472 | 4.6 | IC50 | 25000.0 | Preclinical |
| CHEMBL99050 | 4.45 | IC50 | 35600.0 | Preclinical |
| CHEMBL99229 | 4.44 | IC50 | 36000.0 | Preclinical |
| CHEMBL98696 | 4.42 | IC50 | 38300.0 | Preclinical |
| CHEMBL331385 | 4.41 | IC50 | 39000.0 | Preclinical |
| CHEMBL55595 | 4.41 | IC50 | 39000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 13 | 21 | 4.6 |
| assay format | 7 | 0 | — |
| mitochondrion format | 5 | 0 | — |
| organism-based format | 3 | 0 | — |