Type 1 InsP3 receptor isoform S2 · SINGLE PROTEIN · Sus scrofa
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As of 2026-09-14Protein identity stays anchored to UniProt P79248. Use UniProt P79248 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P79248 as the stable identity anchor, then attach disease evidence before program review.
Type 1 InsP3 receptor isoform S2
Review this target as Type 1 InsP3 receptor isoform S2, mapped to UniProt P79248. Sequence length is 174 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Type 1 InsP3 receptor isoform S2 as ChEMBL target CHEMBL2950, mapped to UniProt P79248. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Type 1 InsP3 receptor isoform S2 is the right protein anchor across sources, using UniProt P79248 as the stable mapping.
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| Preferred Name | Type 1 InsP3 receptor isoform S2 |
| Target Type | SINGLE PROTEIN |
| Organism | Sus scrofa |
| UniProt | P79248 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Type 1 InsP3 receptor isoform S2 |
| UniProt Accession | P79248 |
| Component Type | Protein |
| Sequence Length | 174 aa |
Type 1 InsP3 receptor isoform S2
Review this target as Type 1 InsP3 receptor isoform S2, mapped to UniProt P79248. Sequence length is 174 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL279107 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL1160022 | 7.21 | IC50 | 61.0 | Preclinical |
| CHEMBL351489 | 5.82 | IC50 | 1500.0 | Preclinical |
| CHEMBL1161529 | 5.25 | IC50 | 5652.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 2 | 2 | 6.2 |
| tissue-based format | 2 | 2 | 6.8 |