Adenylate cyclase type 2 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P26769. Use UniProt P26769 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P26769 as the stable identity anchor, then attach disease evidence before program review.
Adenylate cyclase type 2
Review this target as Adenylate cyclase type 2, mapped to UniProt P26769. Sequence length is 1090 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Adenylate cyclase type 2 as ChEMBL target CHEMBL2958, mapped to UniProt P26769. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Adenylate cyclase type 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P26769 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Adenylate cyclase type 2 |
| UniProt Accession | P26769 |
| Component Type | Protein |
| Sequence Length | 1090 aa |
Adenylate cyclase type 2
Review this target as Adenylate cyclase type 2, mapped to UniProt P26769. Sequence length is 1090 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL193521 | 8.94 | IC50 | 1.14 | Preclinical |
| CHEMBL444550 | 6.99 | IC50 | 102.0 | Preclinical |
| CHEMBL2113608 | 6.55 | IC50 | 279.0 | Preclinical |
| CHEMBL611115 | 6.52 | IC50 | 304.0 | Preclinical |
| CHEMBL481858 | 5.4 | IC50 | 4010.0 | Preclinical |
| CHEMBL2113607 | 5.31 | IC50 | 4908.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 0 | — |
| cell membrane format | 1 | 0 | — |
| cell-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 2 | 6 | 6.6 |