D(1A) dopamine receptor · SINGLE PROTEIN · Bos taurus
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As of 2026-09-14Protein identity stays anchored to UniProt Q95136. Use UniProt Q95136 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q95136 as the stable identity anchor, then attach disease evidence before program review.
D(1A) dopamine receptor
Review this target as D(1A) dopamine receptor, mapped to UniProt Q95136. Sequence length is 446 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats D(1A) dopamine receptor as ChEMBL target CHEMBL2967, mapped to UniProt Q95136. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | D(1A) dopamine receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | Q95136 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | D(1A) dopamine receptor |
| UniProt Accession | Q95136 |
| Component Type | Protein |
| Sequence Length | 446 aa |
D(1A) dopamine receptor
Review this target as D(1A) dopamine receptor, mapped to UniProt Q95136. Sequence length is 446 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL62 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL15136 | 8.96 | Ki | 1.1 | Preclinical |
| CHEMBL155596 | 8.52 | Ki | 3.0 | Preclinical |
| CHEMBL59 | 8.15 | Ki | 7.0 | Approved |
| CHEMBL310867 | 7.75 | Ki | 18.0 | Preclinical |
| CHEMBL42055 | 7.75 | Ki | 18.0 | Clinical |
| CHEMBL155613 | 6.96 | Ki | 110.0 | Preclinical |
| CHEMBL559399 | 6.8 | Ki | 160.0 | Preclinical |
| CHEMBL59 | 6.7 | IC50 | 200.0 | Approved |
| CHEMBL168611 | 6.62 | Ki | 240.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 23 | 87 | 5.4 |
| assay format | 14 | 68 | 5.1 |
| tissue-based format | 10 | 35 | 4.6 |
| cell-based format | 6 | 37 | 5.3 |
| cell membrane format | 3 | 23 | 5.2 |