Xaa-Pro aminopeptidase 2 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q99MA2. Use UniProt Q99MA2 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q99MA2 as the stable identity anchor, then attach disease evidence before program review.
Xaa-Pro aminopeptidase 2
Review this target as Xaa-Pro aminopeptidase 2, mapped to UniProt Q99MA2. Sequence length is 674 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Xaa-Pro aminopeptidase 2 as ChEMBL target CHEMBL2970, mapped to UniProt Q99MA2. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Xaa-Pro aminopeptidase 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q99MA2 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Xaa-Pro aminopeptidase 2 |
| UniProt Accession | Q99MA2 |
| Component Type | Protein |
| Sequence Length | 674 aa |
Xaa-Pro aminopeptidase 2
Review this target as Xaa-Pro aminopeptidase 2, mapped to UniProt Q99MA2. Sequence length is 674 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2369858 | 6.51 | IC50 | 310.0 | Preclinical |
| CHEMBL2369868 | 6.25 | IC50 | 560.0 | Preclinical |
| CHEMBL78505 | 6.18 | IC50 | 660.0 | Preclinical |
| CHEMBL79083 | 5.47 | IC50 | 3400.0 | Preclinical |
| CHEMBL311925 | 5.42 | IC50 | 3800.0 | Preclinical |
| CHEMBL311875 | 5.39 | IC50 | 4100.0 | Preclinical |
| CHEMBL79092 | 5.04 | IC50 | 9200.0 | Preclinical |
| CHEMBL81423 | 4.72 | IC50 | 19000.0 | Preclinical |
| CHEMBL80368 | 4.43 | IC50 | 37000.0 | Preclinical |
| CHEMBL309274 | 4.0 | IC50 | 100000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 13 | 5.3 |