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Target Snapshot

CHEMBL2982 Target Snapshot

Adenosine kinase · SINGLE PROTEIN · Toxoplasma gondii

94Compounds
7Assays
1Approved Drugs
151.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q9TVW2. Use UniProt Q9TVW2 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9TVW2 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Adenosine kinase as ChEMBL target CHEMBL2982, mapped to UniProt Q9TVW2. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Adenosine kinase
SINGLE PROTEIN · Toxoplasma gondii
As of 2026-09-14
ChEMBL target ID
CHEMBL2982
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q9TVW2
Adenosine kinase
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Adenosine kinase is the right protein anchor across sources, using UniProt Q9TVW2 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelAdenosine kinase
UniProt AccessionQ9TVW2
Component TypeProtein
Sequence Length363 aa

Adenosine kinase

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Adenosine kinase, mapped to UniProt Q9TVW2. Sequence length is 363 aa.

Mapped IDQ9TVW2
Review nameAdenosine kinase
OrganismToxoplasma gondii
Clinical Profile

Clinical Phase Distribution

1
Approved
Assay Mix

Activity Type Distribution

IC5083.0
KI68.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL61741 6.16 Ki 700.0 Preclinical
CHEMBL61915 6.05 Ki 900.0 Preclinical
CHEMBL418509 5.96 Ki 1100.0 Preclinical
CHEMBL418496 5.92 Ki 1200.0 Preclinical
CHEMBL59168 5.89 Ki 1300.0 Preclinical
CHEMBL292374 5.85 Ki 1400.0 Preclinical
CHEMBL540448 5.82 Ki 1500.0 Preclinical
CHEMBL61387 5.68 Ki 2100.0 Preclinical
CHEMBL60662 5.62 Ki 2400.0 Preclinical
CHEMBL58072 5.6 Ki 2500.0 Preclinical
Distribution

pChEMBL Value Distribution

51
5.0
11
5.5
2
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

7
Total Assays
88
Tested Compounds
1
Assay Types
Binding — 7 assays, 88 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 6 88 4.9
assay format 1 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine