Protein kinase C alpha type · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P17252. Use UniProt P17252 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P17252 as the stable identity anchor, then attach disease evidence before program review.
Protein kinase C alpha type
Review this target as Protein kinase C alpha type, mapped to UniProt P17252. Sequence length is 672 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Protein kinase C alpha type as ChEMBL target CHEMBL299, mapped to UniProt P17252. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Protein kinase C alpha type is the right protein anchor across sources, using UniProt P17252 as the stable mapping.
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| Preferred Name | Protein kinase C alpha type |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P17252 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Protein kinase C alpha type |
| UniProt Accession | P17252 |
| Component Type | Protein |
| Sequence Length | 672 aa |
Protein kinase C alpha type
Review this target as Protein kinase C alpha type, mapped to UniProt P17252. Sequence length is 672 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3892099 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL3893533 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL3895998 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL3920517 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL3932204 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL3943147 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL3951893 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL3957715 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL3958761 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL3958917 | 9.89 | IC50 | 0.13 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 689 | 1,007 | 6.9 |
| cell-based format | 64 | 42 | 6.0 |
| assay format | 54 | 108 | 6.7 |
| subcellular format | 12 | 27 | 6.0 |
| cell membrane format | 2 | 26 | 7.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 5 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |
| single protein format | 1 | 0 | — |