Chymotrypsin-like elastase family member 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9UNI1. Use UniProt Q9UNI1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UNI1 as the stable identity anchor, then attach disease evidence before program review.
Chymotrypsin-like elastase family member 1
Review this target as Chymotrypsin-like elastase family member 1, mapped to UniProt Q9UNI1. Sequence length is 258 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Chymotrypsin-like elastase family member 1 as ChEMBL target CHEMBL3000, mapped to UniProt Q9UNI1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Chymotrypsin-like elastase family member 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UNI1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Chymotrypsin-like elastase family member 1 |
| UniProt Accession | Q9UNI1 |
| Component Type | Protein |
| Sequence Length | 258 aa |
Chymotrypsin-like elastase family member 1
Review this target as Chymotrypsin-like elastase family member 1, mapped to UniProt Q9UNI1. Sequence length is 258 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL130253 | 9.24 | Ki | 0.58 | Preclinical |
| CHEMBL336171 | 9.0 | Ki | 1.0 | Preclinical |
| CHEMBL130271 | 7.85 | Ki | 14.0 | Preclinical |
| CHEMBL231813 | 7.52 | IC50 | 30.0 | Approved |
| CHEMBL337396 | 7.36 | Ki | 44.0 | Preclinical |
| CHEMBL79993 | 7.29 | IC50 | 51.6 | Preclinical |
| CHEMBL446422 | 6.8 | Ki | 160.0 | Preclinical |
| CHEMBL436383 | 6.7 | Ki | 200.0 | Preclinical |
| CHEMBL130128 | 6.6 | Ki | 250.0 | Preclinical |
| CHEMBL465606 | 6.54 | Ki | 290.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 9 | 19 | 6.6 |