5-hydroxytryptamine receptor 2C · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P34968. Use UniProt P34968 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P34968 as the stable identity anchor, then attach disease evidence before program review.
5-hydroxytryptamine receptor 2C
Review this target as 5-hydroxytryptamine receptor 2C, mapped to UniProt P34968. Sequence length is 459 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 5-hydroxytryptamine receptor 2C as ChEMBL target CHEMBL3006, mapped to UniProt P34968. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether 5-hydroxytryptamine receptor 2C is the right protein anchor across sources, using UniProt P34968 as the stable mapping.
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| Preferred Name | 5-hydroxytryptamine receptor 2C |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P34968 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 5-hydroxytryptamine receptor 2C |
| UniProt Accession | P34968 |
| Component Type | Protein |
| Sequence Length | 459 aa |
5-hydroxytryptamine receptor 2C
Review this target as 5-hydroxytryptamine receptor 2C, mapped to UniProt P34968. Sequence length is 459 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL297784 | 8.0 | Ki | 10.0 | Preclinical |
| CHEMBL516 | 7.96 | Ki | 11.0 | Approved |
| CHEMBL47482 | 7.37 | Ki | 43.0 | Preclinical |
| CHEMBL85194 | 6.86 | Ki | 138.04 | Preclinical |
| CHEMBL11 | 6.8 | Ki | 160.0 | Approved |
| CHEMBL3942898 | 5.96 | Ki | 1108.0 | Preclinical |
| CHEMBL323356 | 5.82 | Ki | 1513.56 | Preclinical |
| CHEMBL3946540 | 5.47 | Ki | 3386.0 | Preclinical |
| CHEMBL3986651 | 5.42 | Ki | 3763.0 | Preclinical |
| CHEMBL4112412 | 5.2 | Ki | 6374.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 3 | 7.4 |
| tissue-based format | 2 | 1 | 6.9 |
| assay format | 1 | 5 | 5.4 |
| single protein format | 1 | 2 | 6.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |
| cell-based format | 1 | 0 | — |