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Target Snapshot

CHEMBL3007 Target Snapshot

Sulfotransferase 2A1 · SINGLE PROTEIN · Rattus norvegicus

7Compounds
4Assays
0Approved Drugs
5.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P15709. Use UniProt P15709 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P15709 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Sulfotransferase 2A1 as ChEMBL target CHEMBL3007, mapped to UniProt P15709. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Sulfotransferase 2A1
SINGLE PROTEIN · Rattus norvegicus
As of 2026-09-14
ChEMBL target ID
CHEMBL3007
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P15709
Sulfotransferase 2A1
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Sulfotransferase 2A1 is the right protein anchor across sources, using UniProt P15709 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSulfotransferase 2A1
UniProt AccessionP15709
Component TypeProtein
Sequence Length284 aa

Sulfotransferase 2A1

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Sulfotransferase 2A1, mapped to UniProt P15709. Sequence length is 284 aa.

Mapped IDP15709
Review nameSulfotransferase 2A1
OrganismRattus norvegicus
Clinical Profile

Clinical Phase Distribution

1
Phase III
2
Phase II
1
Phase I
Assay Mix

Activity Type Distribution

IC505.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL150 4.47 IC50 34000.0 Preclinical
CHEMBL44 4.47 IC50 34000.0 Clinical
CHEMBL50 4.47 IC50 34000.0 Clinical
CHEMBL8145 4.47 IC50 34000.0 Clinical
CHEMBL1159897 4.1 IC50 80000.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

4
Total Assays
5
Tested Compounds
1
Assay Types
Binding — 4 assays, 5 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 2 0
single protein format 2 5 4.4

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine