Proto-oncogene tyrosine-protein kinase Src · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q9WUD9. Use UniProt Q9WUD9 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9WUD9 as the stable identity anchor, then attach disease evidence before program review.
Proto-oncogene tyrosine-protein kinase Src
Review this target as Proto-oncogene tyrosine-protein kinase Src, mapped to UniProt Q9WUD9. Sequence length is 536 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Proto-oncogene tyrosine-protein kinase Src as ChEMBL target CHEMBL3014, mapped to UniProt Q9WUD9. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Proto-oncogene tyrosine-protein kinase Src |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q9WUD9 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Proto-oncogene tyrosine-protein kinase Src |
| UniProt Accession | Q9WUD9 |
| Component Type | Protein |
| Sequence Length | 536 aa |
Proto-oncogene tyrosine-protein kinase Src
Review this target as Proto-oncogene tyrosine-protein kinase Src, mapped to UniProt Q9WUD9. Sequence length is 536 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL315575 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL313587 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL85730 | 7.77 | IC50 | 17.0 | Preclinical |
| CHEMBL83069 | 7.6 | IC50 | 25.0 | Preclinical |
| CHEMBL311607 | 7.37 | IC50 | 43.0 | Preclinical |
| CHEMBL83305 | 7.27 | IC50 | 54.0 | Preclinical |
| CHEMBL85011 | 7.25 | IC50 | 56.0 | Preclinical |
| CHEMBL83070 | 7.17 | IC50 | 67.0 | Preclinical |
| CHEMBL314705 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL391738 | 7.14 | IC50 | 73.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 8 | 11 | 6.3 |
| cell-based format | 2 | 13 | 7.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 1 | 7.9 |
| assay format | 1 | 7 | 5.5 |