CDK9/Cyclin K · PROTEIN COMPLEX · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P50750. Use UniProt P50750 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P50750 as the stable identity anchor, then attach disease evidence before program review.
Cyclin-dependent kinase 9
Review this target as CDK9/Cyclin K, mapped to UniProt P50750. ChEMBL maps the protein component as Cyclin-dependent kinase 9. Sequence length is 372 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats CDK9/Cyclin K as ChEMBL target CHEMBL3038475, mapped to UniProt P50750. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether CDK9/Cyclin K is the right protein anchor across sources, using UniProt P50750 as the stable mapping.
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| Preferred Name | CDK9/Cyclin K |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | P50750 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cyclin-dependent kinase 9 |
| UniProt Accession | P50750 |
| Component Type | Protein |
| Sequence Length | 372 aa |
Cyclin-dependent kinase 9
Review this target as CDK9/Cyclin K, mapped to UniProt P50750. ChEMBL maps the protein component as Cyclin-dependent kinase 9. Sequence length is 372 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3656841 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL4287416 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL4293213 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5760232 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5955040 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL1944698 | 8.52 | IC50 | 3.0 | Clinical |
| CHEMBL5961536 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL6043217 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL6058548 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL4281048 | 8.22 | IC50 | 6.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 49 | 51 | 7.1 |
| cell-based format | 9 | 27 | 6.1 |
| assay format | 2 | 1 | 8.5 |