Sialidase-3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9UQ49. Use UniProt Q9UQ49 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UQ49 as the stable identity anchor, then attach disease evidence before program review.
Sialidase-3
Review this target as Sialidase-3, mapped to UniProt Q9UQ49. Sequence length is 428 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sialidase-3 as ChEMBL target CHEMBL3046, mapped to UniProt Q9UQ49. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sialidase-3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UQ49 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sialidase-3 |
| UniProt Accession | Q9UQ49 |
| Component Type | Protein |
| Sequence Length | 428 aa |
Sialidase-3
Review this target as Sialidase-3, mapped to UniProt Q9UQ49. Sequence length is 428 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4076203 | 6.55 | Ki | 280.0 | Preclinical |
| CHEMBL4099818 | 6.5 | Ki | 320.0 | Preclinical |
| CHEMBL4099818 | 6.24 | IC50 | 580.0 | Preclinical |
| CHEMBL222813 | 6.21 | Ki | 620.0 | Approved |
| CHEMBL4064112 | 6.21 | IC50 | 610.0 | Preclinical |
| CHEMBL4076203 | 6.16 | IC50 | 700.0 | Preclinical |
| CHEMBL4062382 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL4071732 | 5.96 | IC50 | 1100.0 | Preclinical |
| CHEMBL96712 | 5.8 | Ki | 1600.0 | Preclinical |
| CHEMBL96712 | 5.62 | IC50 | 2400.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 22 | 77 | 5.1 |
| cell-based format | 12 | 6 | 4.7 |
| single protein format | 7 | 16 | 4.6 |