Nitric oxide synthase, inducible · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q06518. Use UniProt Q06518 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q06518 as the stable identity anchor, then attach disease evidence before program review.
Nitric oxide synthase, inducible
Review this target as Nitric oxide synthase, inducible, mapped to UniProt Q06518. Sequence length is 1147 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Nitric oxide synthase, inducible as ChEMBL target CHEMBL3051, mapped to UniProt Q06518. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Nitric oxide synthase, inducible |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q06518 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Nitric oxide synthase, inducible |
| UniProt Accession | Q06518 |
| Component Type | Protein |
| Sequence Length | 1147 aa |
Nitric oxide synthase, inducible
Review this target as Nitric oxide synthase, inducible, mapped to UniProt Q06518. Sequence length is 1147 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1800346 | 8.74 | Ki | 1.8 | Preclinical |
| CHEMBL4245460 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL11471 | 5.66 | IC50 | 2200.0 | Preclinical |
| CHEMBL1956107 | 5.63 | IC50 | 2340.0 | Preclinical |
| CHEMBL2414836 | 5.01 | IC50 | 9810.0 | Preclinical |
| CHEMBL2414846 | 4.88 | IC50 | 13200.0 | Preclinical |
| CHEMBL2414845 | 4.79 | IC50 | 16200.0 | Preclinical |
| CHEMBL256147 | 4.75 | IC50 | 18000.0 | Clinical |
| CHEMBL233655 | 4.72 | IC50 | 19000.0 | Preclinical |
| CHEMBL227744 | 4.7 | IC50 | 20000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 17 | 8 | 5.3 |
| assay format | 5 | 19 | 4.6 |
| organism-based format | 5 | 0 | — |
| cell-based format | 1 | 1 | 5.6 |