Myosin light chain kinase, smooth muscle · SINGLE PROTEIN · Gallus gallus
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As of 2026-09-13Protein identity stays anchored to UniProt P11799. Use UniProt P11799 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P11799 as the stable identity anchor, then attach disease evidence before program review.
Myosin light chain kinase, smooth muscle
Review this target as Myosin light chain kinase, smooth muscle, mapped to UniProt P11799. Sequence length is 1906 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Myosin light chain kinase, smooth muscle as ChEMBL target CHEMBL3062, mapped to UniProt P11799. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Myosin light chain kinase, smooth muscle |
| Target Type | SINGLE PROTEIN |
| Organism | Gallus gallus |
| UniProt | P11799 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Myosin light chain kinase, smooth muscle |
| UniProt Accession | P11799 |
| Component Type | Protein |
| Sequence Length | 1906 aa |
Myosin light chain kinase, smooth muscle
Review this target as Myosin light chain kinase, smooth muscle, mapped to UniProt P11799. Sequence length is 1906 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL281948 | 10.7 | IC50 | 0.02 | Preclinical |
| CHEMBL522892 | 8.7 | Kd | 2.0 | Clinical |
| CHEMBL388978 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL572878 | 7.82 | Kd | 15.0 | Clinical |
| CHEMBL535 | 7.64 | Kd | 23.0 | Approved |
| CHEMBL385812 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL1721885 | 7.38 | Kd | 42.0 | Clinical |
| CHEMBL443574 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL59384 | 7.09 | IC50 | 82.0 | Preclinical |
| CHEMBL268790 | 6.96 | IC50 | 110.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 19 | 97 | 5.7 |
| assay format | 4 | 1 | 6.6 |