Estrogen receptor · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P19785. Use UniProt P19785 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P19785 as the stable identity anchor, then attach disease evidence before program review.
Estrogen receptor
Review this target as Estrogen receptor, mapped to UniProt P19785. Sequence length is 599 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Estrogen receptor as ChEMBL target CHEMBL3065, mapped to UniProt P19785. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Estrogen receptor is the right protein anchor across sources, using UniProt P19785 as the stable mapping.
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| Preferred Name | Estrogen receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P19785 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Estrogen receptor |
| UniProt Accession | P19785 |
| Component Type | Protein |
| Sequence Length | 599 aa |
Estrogen receptor
Review this target as Estrogen receptor, mapped to UniProt P19785. Sequence length is 599 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL135 | 8.66 | IC50 | 2.2 | Approved |
| CHEMBL2137046 | 7.48 | IC50 | 33.2 | Preclinical |
| CHEMBL188528 | 6.88 | IC50 | 132.0 | Preclinical |
| CHEMBL187207 | 6.7 | IC50 | 199.0 | Preclinical |
| CHEMBL186513 | 6.37 | IC50 | 423.0 | Preclinical |
| CHEMBL450940 | 6.13 | IC50 | 746.0 | Clinical |
| CHEMBL188882 | 5.96 | IC50 | 1089.0 | Preclinical |
| CHEMBL187673 | 5.88 | IC50 | 1335.0 | Preclinical |
| CHEMBL187392 | 5.79 | IC50 | 1629.0 | Preclinical |
| CHEMBL188230 | 5.58 | IC50 | 2601.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 9 | 1 | 7.5 |
| single protein format | 5 | 0 | — |
| assay format | 2 | 9 | 6.4 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 6 | 0 | — |