Gonadotropin-releasing hormone receptor · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P30969. Use UniProt P30969 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P30969 as the stable identity anchor, then attach disease evidence before program review.
Gonadotropin-releasing hormone receptor
Review this target as Gonadotropin-releasing hormone receptor, mapped to UniProt P30969. Sequence length is 327 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Gonadotropin-releasing hormone receptor as ChEMBL target CHEMBL3066, mapped to UniProt P30969. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Gonadotropin-releasing hormone receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P30969 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Gonadotropin-releasing hormone receptor |
| UniProt Accession | P30969 |
| Component Type | Protein |
| Sequence Length | 327 aa |
Gonadotropin-releasing hormone receptor
Review this target as Gonadotropin-releasing hormone receptor, mapped to UniProt P30969. Sequence length is 327 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL409219 | 10.87 | Ki | 0.01349 | Preclinical |
| CHEMBL268397 | 10.63 | Ki | 0.02344 | Preclinical |
| CHEMBL263839 | 10.5 | Ki | 0.03162 | Preclinical |
| CHEMBL263840 | 10.48 | Ki | 0.03311 | Preclinical |
| CHEMBL268319 | 10.28 | Ki | 0.05248 | Preclinical |
| CHEMBL268095 | 10.25 | IC50 | 0.056 | Preclinical |
| CHEMBL409990 | 10.21 | Ki | 0.06166 | Preclinical |
| CHEMBL2370519 | 10.1 | IC50 | 0.08 | Preclinical |
| CHEMBL414113 | 10.1 | Kd | 0.08 | Preclinical |
| CHEMBL414239 | 10.05 | IC50 | 0.09 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 106 | 537 | 7.4 |
| cell membrane format | 14 | 137 | 7.6 |
| cell-based format | 14 | 126 | 8.1 |
| assay format | 8 | 41 | 8.4 |
| organism-based format | 2 | 10 | 5.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 25 | 179 | 6.8 |
| assay format | 9 | 3 | 7.8 |
| organism-based format | 4 | 0 | — |