D(1A) dopamine receptor · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt Q61616. Use UniProt Q61616 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q61616 as the stable identity anchor, then attach disease evidence before program review.
D(1A) dopamine receptor
Review this target as D(1A) dopamine receptor, mapped to UniProt Q61616. Sequence length is 446 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats D(1A) dopamine receptor as ChEMBL target CHEMBL3071, mapped to UniProt Q61616. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | D(1A) dopamine receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q61616 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | D(1A) dopamine receptor |
| UniProt Accession | Q61616 |
| Component Type | Protein |
| Sequence Length | 446 aa |
D(1A) dopamine receptor
Review this target as D(1A) dopamine receptor, mapped to UniProt Q61616. Sequence length is 446 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL62 | 9.4 | Ki | 0.4 | Preclinical |
| CHEMBL3421729 | 7.21 | EC50 | 62.1 | Clinical |
| CHEMBL53 | 7.0 | Ki | 101.0 | Approved |
| CHEMBL4468760 | 6.82 | EC50 | 151.0 | Preclinical |
| CHEMBL263881 | 6.75 | Ki | 180.0 | Clinical |
| CHEMBL137781 | 6.64 | Ki | 230.0 | Preclinical |
| CHEMBL343755 | 6.54 | Ki | 290.0 | Preclinical |
| CHEMBL3421730 | 6.51 | EC50 | 312.0 | Preclinical |
| CHEMBL138989 | 6.47 | Ki | 340.0 | Preclinical |
| CHEMBL40650 | 6.14 | Ki | 717.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 22 | 8 | 6.7 |
| organism-based format | 5 | 0 | — |
| cell-based format | 3 | 9 | 5.8 |
| assay format | 1 | 4 | 5.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 2 | 6.9 |