Chitotriosidase-1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q13231. Use UniProt Q13231 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q13231 as the stable identity anchor, then attach disease evidence before program review.
Chitotriosidase-1
Review this target as Chitotriosidase-1, mapped to UniProt Q13231. Sequence length is 466 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Chitotriosidase-1 as ChEMBL target CHEMBL3080, mapped to UniProt Q13231. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Chitotriosidase-1 is the right protein anchor across sources, using UniProt Q13231 as the stable mapping.
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| Preferred Name | Chitotriosidase-1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q13231 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Chitotriosidase-1 |
| UniProt Accession | Q13231 |
| Component Type | Protein |
| Sequence Length | 466 aa |
Chitotriosidase-1
Review this target as Chitotriosidase-1, mapped to UniProt Q13231. Sequence length is 466 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1738785 | 8.85 | Ki | 1.4 | Preclinical |
| CHEMBL4776610 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL4756869 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL4788866 | 7.76 | Ki | 17.3 | Clinical |
| CHEMBL4794014 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL4464754 | 7.68 | IC50 | 21.0 | Preclinical |
| CHEMBL4755139 | 7.66 | IC50 | 22.0 | Preclinical |
| CHEMBL4789376 | 7.66 | IC50 | 22.0 | Preclinical |
| CHEMBL4764430 | 7.64 | IC50 | 23.0 | Preclinical |
| CHEMBL4788866 | 7.64 | IC50 | 23.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 14 | 108 | 5.4 |
| cell-based format | 8 | 94 | 6.4 |
| assay format | 6 | 3 | 6.4 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 0 | — |