Use UniProt Q5SWU9 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3086 Target Snapshot
Acetyl-CoA carboxylase 1 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q5SWU9. Use UniProt Q5SWU9 as the stable identity anchor, then attach disease evidence before program review.
Acetyl-CoA carboxylase 1
Review this target as Acetyl-CoA carboxylase 1, mapped to UniProt Q5SWU9. Sequence length is 2345 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Acetyl-CoA carboxylase 1 as ChEMBL target CHEMBL3086, mapped to UniProt Q5SWU9. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Acetyl-CoA carboxylase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q5SWU9 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Acetyl-CoA carboxylase 1 |
| UniProt Accession | Q5SWU9 |
| Component Type | Protein |
| Sequence Length | 2345 aa |
Acetyl-CoA carboxylase 1
How to read this target
Review this target as Acetyl-CoA carboxylase 1, mapped to UniProt Q5SWU9. Sequence length is 2345 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4060253 | 9.74 | IC50 | 0.18 | Preclinical |
| CHEMBL4528475 | 8.41 | IC50 | 3.9 | Preclinical |
| CHEMBL3110076 | 6.37 | IC50 | 427.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 5 assays, 3 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 0 | — |
| cell-based format | 2 | 2 | 9.1 |
| single protein format | 1 | 1 | 6.4 |
Functional — 1 assays, 0 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 1 | 0 | — |