GMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase · SINGLE PROTEIN · Macaca mulatta
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As of 2026-09-14Protein identity stays anchored to UniProt B3VTJ2. Use UniProt B3VTJ2 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt B3VTJ2 as the stable identity anchor, then attach disease evidence before program review.
Phosphodiesterase
Review this target as GMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase, mapped to UniProt B3VTJ2. ChEMBL maps the protein component as Phosphodiesterase. Sequence length is 941 aa.
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This review treats GMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase as ChEMBL target CHEMBL3091263, mapped to UniProt B3VTJ2. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | GMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase |
| Target Type | SINGLE PROTEIN |
| Organism | Macaca mulatta |
| UniProt | B3VTJ2 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phosphodiesterase |
| UniProt Accession | B3VTJ2 |
| Component Type | Protein |
| Sequence Length | 941 aa |
Phosphodiesterase
Review this target as GMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase, mapped to UniProt B3VTJ2. ChEMBL maps the protein component as Phosphodiesterase. Sequence length is 941 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3092564 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL5847109 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL5830637 | 9.96 | Ki | 0.11 | Preclinical |
| CHEMBL5847051 | 9.96 | Ki | 0.11 | Preclinical |
| CHEMBL5922620 | 9.96 | Ki | 0.11 | Preclinical |
| CHEMBL6029690 | 9.96 | Ki | 0.11 | Preclinical |
| CHEMBL5744255 | 9.92 | Ki | 0.12 | Preclinical |
| CHEMBL5915385 | 9.92 | Ki | 0.12 | Preclinical |
| CHEMBL5876913 | 9.85 | Ki | 0.14 | Preclinical |
| CHEMBL5940967 | 9.85 | Ki | 0.14 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 6 | 722 | 7.6 |
| single protein format | 2 | 23 | 6.7 |
| cell-based format | 1 | 5 | 9.3 |