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Target Snapshot

CHEMBL3091269 Target Snapshot

NAD(P)H dehydrogenase [quinone] 1 · SINGLE PROTEIN · Rattus norvegicus

3Compounds
2Assays
1Approved Drugs
1.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P05982. Use UniProt P05982 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P05982 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats NAD(P)H dehydrogenase [quinone] 1 as ChEMBL target CHEMBL3091269, mapped to UniProt P05982. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
NAD(P)H dehydrogenase [quinone] 1
SINGLE PROTEIN · Rattus norvegicus
As of 2026-09-14
ChEMBL target ID
CHEMBL3091269
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P05982
NAD(P)H dehydrogenase [quinone] 1
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether NAD(P)H dehydrogenase [quinone] 1 is the right protein anchor across sources, using UniProt P05982 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelNAD(P)H dehydrogenase [quinone] 1
UniProt AccessionP05982
Component TypeProtein
Sequence Length274 aa

NAD(P)H dehydrogenase [quinone] 1

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as NAD(P)H dehydrogenase [quinone] 1, mapped to UniProt P05982. Sequence length is 274 aa.

Mapped IDP05982
Review nameNAD(P)H dehydrogenase [quinone] 1
OrganismRattus norvegicus
Clinical Profile

Clinical Phase Distribution

1
Approved
Assay Mix

Activity Type Distribution

KI1.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1466 9.0 Ki 1.0 Approved
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
1
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

DICUMAROL
CHEMBL1466
Approved 1944
Assay Landscape

Assay Landscape

2
Total Assays
1
Tested Compounds
1
Assay Types
Binding — 2 assays, 1 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 1 1 9.0
single protein format 1 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine