Acetylcholine receptor subunit alpha · SINGLE PROTEIN · Torpedo californica
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As of 2026-09-13Protein identity stays anchored to UniProt P02710. Use UniProt P02710 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P02710 as the stable identity anchor, then attach disease evidence before program review.
Acetylcholine receptor subunit alpha
Review this target as Acetylcholine receptor subunit alpha, mapped to UniProt P02710. Sequence length is 461 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Acetylcholine receptor subunit alpha as ChEMBL target CHEMBL3097, mapped to UniProt P02710. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Acetylcholine receptor subunit alpha |
| Target Type | SINGLE PROTEIN |
| Organism | Torpedo californica |
| UniProt | P02710 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Acetylcholine receptor subunit alpha |
| UniProt Accession | P02710 |
| Component Type | Protein |
| Sequence Length | 461 aa |
Acetylcholine receptor subunit alpha
Review this target as Acetylcholine receptor subunit alpha, mapped to UniProt P02710. Sequence length is 461 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL275528 | 6.66 | IC50 | 217.0 | Clinical |
| CHEMBL279676 | 6.62 | IC50 | 237.0 | Clinical |
| CHEMBL59986 | 6.5 | Ki | 314.0 | Preclinical |
| CHEMBL262769 | 6.42 | Ki | 384.0 | Preclinical |
| CHEMBL267936 | 6.22 | IC50 | 596.0 | Approved |
| CHEMBL122270 | 6.0 | IC50 | 1010.0 | Clinical |
| CHEMBL71 | 5.89 | IC50 | 1280.0 | Approved |
| CHEMBL430497 | 5.47 | Ki | 3400.0 | Clinical |
| CHEMBL497939 | 5.45 | IC50 | 3530.0 | Clinical |
| CHEMBL742 | 5.3 | IC50 | 4950.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 17 | 20 | 5.3 |
| single protein format | 8 | 9 | 5.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |