Transient receptor potential cation channel subfamily M member 8 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q8R4D5. Use UniProt Q8R4D5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8R4D5 as the stable identity anchor, then attach disease evidence before program review.
Transient receptor potential cation channel subfamily M member 8
Review this target as Transient receptor potential cation channel subfamily M member 8, mapped to UniProt Q8R4D5. Sequence length is 1104 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Transient receptor potential cation channel subfamily M member 8 as ChEMBL target CHEMBL3108632, mapped to UniProt Q8R4D5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Transient receptor potential cation channel subfamily M member 8 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q8R4D5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Transient receptor potential cation channel subfamily M member 8 |
| UniProt Accession | Q8R4D5 |
| Component Type | Protein |
| Sequence Length | 1104 aa |
Transient receptor potential cation channel subfamily M member 8
Review this target as Transient receptor potential cation channel subfamily M member 8, mapped to UniProt Q8R4D5. Sequence length is 1104 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4247840 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL4243837 | 8.05 | IC50 | 9.0 | Preclinical |
| CHEMBL4248077 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL4251467 | 7.77 | IC50 | 17.0 | Preclinical |
| CHEMBL4238921 | 7.62 | IC50 | 24.0 | Preclinical |
| CHEMBL4251427 | 7.57 | IC50 | 27.0 | Preclinical |
| CHEMBL4247268 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL4247395 | 7.37 | IC50 | 43.0 | Preclinical |
| CHEMBL4246904 | 7.31 | IC50 | 49.0 | Preclinical |
| CHEMBL4245257 | 7.28 | IC50 | 53.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 44 | 38 | 6.3 |
| assay format | 1 | 0 | — |