Arginase · SINGLE PROTEIN · Leishmania amazonensis
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As of 2026-09-14Protein identity stays anchored to UniProt O96394. Use UniProt O96394 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O96394 as the stable identity anchor, then attach disease evidence before program review.
Arginase
Review this target as Arginase, mapped to UniProt O96394. Sequence length is 329 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Arginase as ChEMBL target CHEMBL3108635, mapped to UniProt O96394. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Arginase is the right protein anchor across sources, using UniProt O96394 as the stable mapping.
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| Preferred Name | Arginase |
| Target Type | SINGLE PROTEIN |
| Organism | Leishmania amazonensis |
| UniProt | O96394 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Arginase |
| UniProt Accession | O96394 |
| Component Type | Protein |
| Sequence Length | 329 aa |
Arginase
Review this target as Arginase, mapped to UniProt O96394. Sequence length is 329 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL583912 | 6.7 | Ki | 200.0 | Clinical |
| CHEMBL311498 | 6.22 | Ki | 600.0 | Approved |
| CHEMBL444478 | 6.16 | Ki | 700.0 | Clinical |
| CHEMBL3109443 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL3109443 | 6.05 | Ki | 900.0 | Preclinical |
| CHEMBL164 | 5.92 | Ki | 1200.0 | Preclinical |
| CHEMBL3098862 | 5.89 | Ki | 1300.0 | Preclinical |
| CHEMBL4204512 | 5.89 | Ki | 1300.0 | Preclinical |
| CHEMBL31574 | 5.85 | IC50 | 1400.0 | Clinical |
| CHEMBL583912 | 5.8 | IC50 | 1600.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 13 | 27 | 5.2 |
| single protein format | 5 | 10 | 5.2 |