Use UniProt Q9BXF3 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3108639 Target Snapshot
Chromatin remodeling regulator CECR2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9BXF3. Use UniProt Q9BXF3 as the stable identity anchor, then attach disease evidence before program review.
Chromatin remodeling regulator CECR2
Review this target as Chromatin remodeling regulator CECR2, mapped to UniProt Q9BXF3. Sequence length is 1484 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Chromatin remodeling regulator CECR2 as ChEMBL target CHEMBL3108639, mapped to UniProt Q9BXF3. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Chromatin remodeling regulator CECR2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9BXF3 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Chromatin remodeling regulator CECR2 |
| UniProt Accession | Q9BXF3 |
| Component Type | Protein |
| Sequence Length | 1484 aa |
Chromatin remodeling regulator CECR2
How to read this target
Review this target as Chromatin remodeling regulator CECR2, mapped to UniProt Q9BXF3. Sequence length is 1484 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3823478 | 9.0 | Kd | 1.0 | Preclinical |
| CHEMBL4465880 | 8.2 | IC50 | 6.31 | Preclinical |
| CHEMBL3133807 | 8.1 | Kd | 8.0 | Preclinical |
| CHEMBL4577486 | 8.1 | Kd | 7.943 | Preclinical |
| CHEMBL3133807 | 8.03 | IC50 | 9.4 | Preclinical |
| CHEMBL4461619 | 8.0 | Kd | 10.0 | Preclinical |
| CHEMBL4465880 | 8.0 | Kd | 10.0 | Preclinical |
| CHEMBL4586175 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL4513694 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL4520419 | 7.96 | IC50 | 11.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 130 assays, 186 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 91 | 147 | 6.3 |
| assay format | 29 | 11 | 6.3 |
| cell-based format | 10 | 28 | 6.9 |
Functional — 1 assays, 1 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 1 | 7.5 |