Glutamate receptor ionotropic, NMDA 2B · SINGLE PROTEIN · Rattus norvegicus
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q00960. Use UniProt Q00960 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q00960 as the stable identity anchor, then attach disease evidence before program review.
Glutamate receptor ionotropic, NMDA 2B
Review this target as Glutamate receptor ionotropic, NMDA 2B, mapped to UniProt Q00960. Sequence length is 1482 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Glutamate receptor ionotropic, NMDA 2B as ChEMBL target CHEMBL311, mapped to UniProt Q00960. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Glutamate receptor ionotropic, NMDA 2B is the right protein anchor across sources, using UniProt Q00960 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Glutamate receptor ionotropic, NMDA 2B |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q00960 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glutamate receptor ionotropic, NMDA 2B |
| UniProt Accession | Q00960 |
| Component Type | Protein |
| Sequence Length | 1482 aa |
Glutamate receptor ionotropic, NMDA 2B
Review this target as Glutamate receptor ionotropic, NMDA 2B, mapped to UniProt Q00960. Sequence length is 1482 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL219986 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL5569595 | 8.95 | Ki | 1.12 | Preclinical |
| CHEMBL220611 | 8.92 | IC50 | 1.2 | Preclinical |
| CHEMBL424752 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL5410727 | 8.89 | Ki | 1.3 | Preclinical |
| CHEMBL5595448 | 8.89 | Ki | 1.28 | Preclinical |
| CHEMBL5574644 | 8.87 | Ki | 1.34 | Preclinical |
| CHEMBL4111330 | 8.85 | Ki | 1.4 | Preclinical |
| CHEMBL4115628 | 8.85 | Ki | 1.4 | Preclinical |
| CHEMBL4109878 | 8.82 | Ki | 1.5 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 43 | 77 | 6.8 |
| assay format | 10 | 230 | 7.3 |
| cell membrane format | 10 | 148 | 7.5 |
| cell-based format | 10 | 46 | 4.7 |
| single protein format | 6 | 71 | 7.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 6 | 54 | 7.2 |