Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q96Q83. Use UniProt Q96Q83 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q96Q83 as the stable identity anchor, then attach disease evidence before program review.
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3
Review this target as Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, mapped to UniProt Q96Q83. Sequence length is 286 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 as ChEMBL target CHEMBL3112376, mapped to UniProt Q96Q83. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q96Q83 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 |
| UniProt Accession | Q96Q83 |
| Component Type | Protein |
| Sequence Length | 286 aa |
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3
Review this target as Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, mapped to UniProt Q96Q83. Sequence length is 286 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3145429 | 6.32 | IC50 | 480.0 | Preclinical |
| CHEMBL3145446 | 6.31 | IC50 | 490.0 | Preclinical |
| CHEMBL3145436 | 6.27 | IC50 | 540.0 | Preclinical |
| CHEMBL3145440 | 6.26 | IC50 | 550.0 | Preclinical |
| CHEMBL3145451 | 6.24 | IC50 | 570.0 | Preclinical |
| CHEMBL3145441 | 6.22 | IC50 | 600.0 | Preclinical |
| CHEMBL3145447 | 6.21 | IC50 | 610.0 | Preclinical |
| CHEMBL3145442 | 6.2 | IC50 | 630.0 | Preclinical |
| CHEMBL3145448 | 6.19 | IC50 | 640.0 | Preclinical |
| CHEMBL3115002 | 6.17 | IC50 | 670.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 18 | 47 | 5.6 |
| cell-based format | 3 | 9 | 4.8 |
| assay format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 1 | 6.2 |