Phosphatidylcholine:ceramide cholinephosphotransferase 2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q8NHU3. Use UniProt Q8NHU3 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8NHU3 as the stable identity anchor, then attach disease evidence before program review.
Phosphatidylcholine:ceramide cholinephosphotransferase 2
Review this target as Phosphatidylcholine:ceramide cholinephosphotransferase 2, mapped to UniProt Q8NHU3. Sequence length is 365 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Phosphatidylcholine:ceramide cholinephosphotransferase 2 as ChEMBL target CHEMBL3112379, mapped to UniProt Q8NHU3. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Phosphatidylcholine:ceramide cholinephosphotransferase 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8NHU3 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phosphatidylcholine:ceramide cholinephosphotransferase 2 |
| UniProt Accession | Q8NHU3 |
| Component Type | Protein |
| Sequence Length | 365 aa |
Phosphatidylcholine:ceramide cholinephosphotransferase 2
Review this target as Phosphatidylcholine:ceramide cholinephosphotransferase 2, mapped to UniProt Q8NHU3. Sequence length is 365 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4172856 | 8.19 | IC50 | 6.5 | Preclinical |
| CHEMBL4177314 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL4172856 | 7.55 | Kd | 28.0 | Preclinical |
| CHEMBL4646354 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL4645607 | 7.35 | IC50 | 45.0 | Preclinical |
| CHEMBL4641888 | 7.33 | IC50 | 47.0 | Preclinical |
| CHEMBL4203399 | 7.05 | IC50 | 90.0 | Preclinical |
| CHEMBL4540510 | 7.04 | IC50 | 91.0 | Preclinical |
| CHEMBL4638337 | 7.04 | IC50 | 91.0 | Preclinical |
| CHEMBL4204352 | 7.0 | IC50 | 100.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 21 | 43 | 5.8 |
| single protein format | 7 | 36 | 6.0 |
| subcellular format | 2 | 36 | 5.5 |