Retinal dehydrogenase 2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O94788. Use UniProt O94788 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O94788 as the stable identity anchor, then attach disease evidence before program review.
Retinal dehydrogenase 2
Review this target as Retinal dehydrogenase 2, mapped to UniProt O94788. Sequence length is 518 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Retinal dehydrogenase 2 as ChEMBL target CHEMBL3112384, mapped to UniProt O94788. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Retinal dehydrogenase 2 is the right protein anchor across sources, using UniProt O94788 as the stable mapping.
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| Preferred Name | Retinal dehydrogenase 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O94788 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Retinal dehydrogenase 2 |
| UniProt Accession | O94788 |
| Component Type | Protein |
| Sequence Length | 518 aa |
Retinal dehydrogenase 2
Review this target as Retinal dehydrogenase 2, mapped to UniProt O94788. Sequence length is 518 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4849586 | 7.68 | IC50 | 21.0 | Preclinical |
| CHEMBL4876602 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL3276621 | 7.25 | Ki | 56.0 | Preclinical |
| CHEMBL4846203 | 7.24 | IC50 | 58.0 | Preclinical |
| CHEMBL4875157 | 7.2 | IC50 | 63.0 | Preclinical |
| CHEMBL4090473 | 7.19 | IC50 | 65.0 | Preclinical |
| CHEMBL4286209 | 7.19 | Ki | 64.35 | Preclinical |
| CHEMBL4847114 | 7.19 | IC50 | 65.0 | Preclinical |
| CHEMBL1562069 | 7.16 | IC50 | 69.0 | Preclinical |
| CHEMBL4859904 | 7.1 | IC50 | 80.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 27 | 69 | 6.2 |
| assay format | 5 | 10 | 6.1 |