HTH-type quorum-sensing regulator RhlR · SINGLE PROTEIN · Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P54292. Use UniProt P54292 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P54292 as the stable identity anchor, then attach disease evidence before program review.
HTH-type quorum-sensing regulator RhlR
Review this target as HTH-type quorum-sensing regulator RhlR, mapped to UniProt P54292. Sequence length is 241 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats HTH-type quorum-sensing regulator RhlR as ChEMBL target CHEMBL3112386, mapped to UniProt P54292. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether HTH-type quorum-sensing regulator RhlR is the right protein anchor across sources, using UniProt P54292 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | HTH-type quorum-sensing regulator RhlR |
| Target Type | SINGLE PROTEIN |
| Organism | Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) |
| UniProt | P54292 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | HTH-type quorum-sensing regulator RhlR |
| UniProt Accession | P54292 |
| Component Type | Protein |
| Sequence Length | 241 aa |
HTH-type quorum-sensing regulator RhlR
Review this target as HTH-type quorum-sensing regulator RhlR, mapped to UniProt P54292. Sequence length is 241 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5266949 | 5.99 | EC50 | 1020.0 | Preclinical |
| CHEMBL5291457 | 5.85 | EC50 | 1410.0 | Preclinical |
| CHEMBL4098007 | 5.69 | IC50 | 2030.0 | Preclinical |
| CHEMBL5267863 | 5.42 | EC50 | 3820.0 | Preclinical |
| CHEMBL4292339 | 5.1 | IC50 | 8000.0 | Preclinical |
| CHEMBL3793369 | 4.9 | IC50 | 12500.0 | Preclinical |
| CHEMBL4642992 | 4.58 | IC50 | 26000.0 | Preclinical |
| CHEMBL122890 | 4.3 | IC50 | 50000.0 | Preclinical |
| CHEMBL4632586 | 4.07 | IC50 | 86000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 20 | 5 | 5.4 |
| assay format | 13 | 8 | 4.8 |