Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 · SINGLE PROTEIN · Homo sapiens
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt O14983. Use UniProt O14983 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O14983 as the stable identity anchor, then attach disease evidence before program review.
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Review this target as Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, mapped to UniProt O14983. Sequence length is 1001 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 as ChEMBL target CHEMBL3136, mapped to UniProt O14983. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 is the right protein anchor across sources, using UniProt O14983 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O14983 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 |
| UniProt Accession | O14983 |
| Component Type | Protein |
| Sequence Length | 1001 aa |
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Review this target as Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, mapped to UniProt O14983. Sequence length is 1001 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL96926 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL365703 | 8.92 | IC50 | 1.2 | Preclinical |
| CHEMBL191633 | 8.68 | IC50 | 2.08 | Preclinical |
| CHEMBL4216774 | 7.77 | Ki | 17.0 | Preclinical |
| CHEMBL4207081 | 7.72 | Ki | 19.0 | Preclinical |
| CHEMBL191927 | 7.7 | IC50 | 19.83 | Preclinical |
| CHEMBL480627 | 5.75 | Ki | 1800.0 | Preclinical |
| CHEMBL362947 | 5.04 | IC50 | 9038.0 | Preclinical |
| CHEMBL13045 | 4.57 | IC50 | 27000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 9 | 7.3 |