Use UniProt Q11128 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3146 Target Snapshot
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q11128. Use UniProt Q11128 as the stable identity anchor, then attach disease evidence before program review.
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5
Review this target as 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5, mapped to UniProt Q11128. Sequence length is 374 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 as ChEMBL target CHEMBL3146, mapped to UniProt Q11128. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 is the right protein anchor across sources, using UniProt Q11128 as the stable mapping.
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| Preferred Name | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q11128 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 |
| UniProt Accession | Q11128 |
| Component Type | Protein |
| Sequence Length | 374 aa |
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5
How to read this target
Review this target as 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5, mapped to UniProt Q11128. Sequence length is 374 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1170899 | 5.01 | Ki | 9700.0 | Preclinical |
| CHEMBL1170899 | 4.95 | IC50 | 11300.0 | Preclinical |
| CHEMBL52741 | 4.35 | IC50 | 45000.0 | Preclinical |
| CHEMBL384759 | 4.17 | IC50 | 67000.0 | Preclinical |
| CHEMBL609638 | 4.17 | Ki | 67100.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 9 assays, 5 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 9 | 5 | 4.5 |