Use UniProt P34978 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3156 Target Snapshot
Thromboxane A2 receptor · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P34978. Use UniProt P34978 as the stable identity anchor, then attach disease evidence before program review.
Thromboxane A2 receptor
Review this target as Thromboxane A2 receptor, mapped to UniProt P34978. Sequence length is 341 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Thromboxane A2 receptor as ChEMBL target CHEMBL3156, mapped to UniProt P34978. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Thromboxane A2 receptor is the right protein anchor across sources, using UniProt P34978 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Thromboxane A2 receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P34978 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Thromboxane A2 receptor |
| UniProt Accession | P34978 |
| Component Type | Protein |
| Sequence Length | 341 aa |
Thromboxane A2 receptor
How to read this target
Review this target as Thromboxane A2 receptor, mapped to UniProt P34978. Sequence length is 341 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL65478 | 10.8 | Kd | 0.01585 | Preclinical |
| CHEMBL62666 | 10.6 | Kd | 0.02512 | Preclinical |
| CHEMBL66194 | 10.6 | Kd | 0.02512 | Preclinical |
| CHEMBL65780 | 10.4 | Kd | 0.03981 | Preclinical |
| CHEMBL65167 | 10.2 | Kd | 0.0631 | Preclinical |
| CHEMBL65571 | 10.2 | Kd | 0.0631 | Preclinical |
| CHEMBL102533 | 10.13 | Kd | 0.07413 | Preclinical |
| CHEMBL303097 | 10.1 | Kd | 0.07943 | Preclinical |
| CHEMBL65175 | 10.0 | Kd | 0.1 | Preclinical |
| CHEMBL43770 | 9.76 | Kd | 0.1738 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Functional — 20 assays, 133 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 15 | 74 | 7.6 |
| assay format | 5 | 59 | 7.5 |
Binding — 6 assays, 5 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 3 | 0 | — |
| tissue-based format | 2 | 4 | 8.1 |
| assay format | 1 | 1 | 8.4 |