Thymidylate synthase · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P07607. Use UniProt P07607 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P07607 as the stable identity anchor, then attach disease evidence before program review.
Thymidylate synthase
Review this target as Thymidylate synthase, mapped to UniProt P07607. Sequence length is 307 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Thymidylate synthase as ChEMBL target CHEMBL3160, mapped to UniProt P07607. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Thymidylate synthase is the right protein anchor across sources, using UniProt P07607 as the stable mapping.
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| Preferred Name | Thymidylate synthase |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P07607 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Thymidylate synthase |
| UniProt Accession | P07607 |
| Component Type | Protein |
| Sequence Length | 307 aa |
Thymidylate synthase
Review this target as Thymidylate synthase, mapped to UniProt P07607. Sequence length is 307 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL349432 | 9.92 | Ki | 0.12 | Preclinical |
| CHEMBL320217 | 9.77 | Ki | 0.17 | Preclinical |
| CHEMBL102143 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL61300 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL30179 | 9.68 | Ki | 0.21 | Preclinical |
| CHEMBL299273 | 9.59 | Ki | 0.26 | Preclinical |
| CHEMBL1202139 | 9.57 | Ki | 0.27 | Preclinical |
| CHEMBL323098 | 9.48 | Ki | 0.33 | Preclinical |
| CHEMBL35926 | 9.46 | Ki | 0.35 | Preclinical |
| CHEMBL160498 | 9.4 | IC50 | 0.4 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 60 | 312 | 7.0 |
| single protein format | 30 | 181 | 6.3 |
| assay format | 2 | 4 | 7.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 15 | 0 | — |
| cell-based format | 1 | 5 | 7.1 |