Insulin receptor · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P15208. Use UniProt P15208 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P15208 as the stable identity anchor, then attach disease evidence before program review.
Insulin receptor
Review this target as Insulin receptor, mapped to UniProt P15208. Sequence length is 1372 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Insulin receptor as ChEMBL target CHEMBL3187, mapped to UniProt P15208. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Insulin receptor is the right protein anchor across sources, using UniProt P15208 as the stable mapping.
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| Preferred Name | Insulin receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P15208 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Insulin receptor |
| UniProt Accession | P15208 |
| Component Type | Protein |
| Sequence Length | 1372 aa |
Insulin receptor
Review this target as Insulin receptor, mapped to UniProt P15208. Sequence length is 1372 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4226003 | 8.4 | EC50 | 4.0 | Preclinical |
| CHEMBL551064 | 6.85 | IC50 | 140.0 | Preclinical |
| CHEMBL388978 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL2037224 | 5.54 | IC50 | 2900.0 | Preclinical |
| CHEMBL1627107 | 5.3 | EC50 | 5000.0 | Preclinical |
| CHEMBL2037211 | 5.27 | IC50 | 5400.0 | Preclinical |
| CHEMBL2037209 | 5.24 | IC50 | 5700.0 | Preclinical |
| CHEMBL2037208 | 5.24 | IC50 | 5800.0 | Preclinical |
| CHEMBL500606 | 5.22 | EC50 | 6000.0 | Preclinical |
| CHEMBL340520 | 5.17 | IC50 | 6700.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 11 | 0 | — |
| cell-based format | 1 | 3 | 5.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 9 | 32 | 4.8 |
| single protein format | 1 | 1 | 8.4 |