Sodium- and chloride-dependent glycine transporter 2 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P58295. Use UniProt P58295 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P58295 as the stable identity anchor, then attach disease evidence before program review.
Sodium- and chloride-dependent glycine transporter 2
Review this target as Sodium- and chloride-dependent glycine transporter 2, mapped to UniProt P58295. Sequence length is 799 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sodium- and chloride-dependent glycine transporter 2 as ChEMBL target CHEMBL3195, mapped to UniProt P58295. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sodium- and chloride-dependent glycine transporter 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P58295 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sodium- and chloride-dependent glycine transporter 2 |
| UniProt Accession | P58295 |
| Component Type | Protein |
| Sequence Length | 799 aa |
Sodium- and chloride-dependent glycine transporter 2
Review this target as Sodium- and chloride-dependent glycine transporter 2, mapped to UniProt P58295. Sequence length is 799 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1649969 | 6.96 | IC50 | 110.0 | Preclinical |
| CHEMBL28578 | 6.82 | IC50 | 150.0 | Preclinical |
| CHEMBL1649974 | 6.64 | IC50 | 230.0 | Preclinical |
| CHEMBL1649956 | 6.58 | IC50 | 260.0 | Preclinical |
| CHEMBL1649954 | 6.55 | IC50 | 280.0 | Preclinical |
| CHEMBL29608 | 6.55 | IC50 | 283.0 | Preclinical |
| CHEMBL29220 | 6.54 | IC50 | 290.0 | Preclinical |
| CHEMBL28746 | 6.48 | IC50 | 330.0 | Preclinical |
| CHEMBL1649588 | 6.47 | IC50 | 340.0 | Preclinical |
| CHEMBL2419425 | 6.47 | IC50 | 340.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 23 | 6.1 |
| assay format | 1 | 6 | 5.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 26 | 5.9 |