Acetylcholinesterase · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P37136. Use UniProt P37136 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P37136 as the stable identity anchor, then attach disease evidence before program review.
Acetylcholinesterase
Review this target as Acetylcholinesterase, mapped to UniProt P37136. Sequence length is 614 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Acetylcholinesterase as ChEMBL target CHEMBL3199, mapped to UniProt P37136. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Acetylcholinesterase |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P37136 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Acetylcholinesterase |
| UniProt Accession | P37136 |
| Component Type | Protein |
| Sequence Length | 614 aa |
Acetylcholinesterase
Review this target as Acetylcholinesterase, mapped to UniProt P37136. Sequence length is 614 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL307004 | 10.15 | IC50 | 0.07 | Preclinical |
| CHEMBL4066593 | 10.15 | IC50 | 0.07 | Preclinical |
| CHEMBL32823 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL4080023 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL312310 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL340427 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL4104258 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL106739 | 9.42 | IC50 | 0.38 | Preclinical |
| CHEMBL73800 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL117521 | 9.4 | IC50 | 0.4 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 125 | 887 | 6.2 |
| tissue-based format | 57 | 317 | 6.5 |
| single protein format | 33 | 279 | 6.6 |
| organism-based format | 19 | 0 | — |
| cell-based format | 2 | 10 | 4.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 9 | 1 | 4.5 |
| organism-based format | 6 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 5 | 15 | 4.7 |