4-hydroxyphenylpyruvate dioxygenase · SINGLE PROTEIN · Sus scrofa
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As of 2026-09-14Protein identity stays anchored to UniProt Q02110. Use UniProt Q02110 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q02110 as the stable identity anchor, then attach disease evidence before program review.
4-hydroxyphenylpyruvate dioxygenase
Review this target as 4-hydroxyphenylpyruvate dioxygenase, mapped to UniProt Q02110. Sequence length is 393 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 4-hydroxyphenylpyruvate dioxygenase as ChEMBL target CHEMBL3203, mapped to UniProt Q02110. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether 4-hydroxyphenylpyruvate dioxygenase is the right protein anchor across sources, using UniProt Q02110 as the stable mapping.
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| Preferred Name | 4-hydroxyphenylpyruvate dioxygenase |
| Target Type | SINGLE PROTEIN |
| Organism | Sus scrofa |
| UniProt | Q02110 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 4-hydroxyphenylpyruvate dioxygenase |
| UniProt Accession | Q02110 |
| Component Type | Protein |
| Sequence Length | 393 aa |
4-hydroxyphenylpyruvate dioxygenase
Review this target as 4-hydroxyphenylpyruvate dioxygenase, mapped to UniProt Q02110. Sequence length is 393 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL309664 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL76394 | 7.55 | IC50 | 28.0 | Preclinical |
| CHEMBL23622 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL1337 | 7.4 | IC50 | 40.0 | Approved |
| CHEMBL23996 | 7.4 | IC50 | 39.81 | Preclinical |
| CHEMBL308262 | 7.4 | IC50 | 39.81 | Preclinical |
| CHEMBL73467 | 7.35 | IC50 | 44.67 | Preclinical |
| CHEMBL72081 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL307048 | 7.05 | IC50 | 89.13 | Preclinical |
| CHEMBL26162 | 6.96 | IC50 | 109.65 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 14 | 67 | 6.0 |
| single protein format | 3 | 9 | 4.7 |