CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q02734. Use UniProt Q02734 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q02734 as the stable identity anchor, then attach disease evidence before program review.
CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase
Review this target as CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase, mapped to UniProt Q02734. Sequence length is 374 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase as ChEMBL target CHEMBL3211, mapped to UniProt Q02734. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q02734 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase |
| UniProt Accession | Q02734 |
| Component Type | Protein |
| Sequence Length | 374 aa |
CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase
Review this target as CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase, mapped to UniProt Q02734. Sequence length is 374 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4798770 | 6.11 | IC50 | 770.0 | Preclinical |
| CHEMBL4785533 | 6.1 | IC50 | 800.0 | Preclinical |
| CHEMBL3596261 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL4785375 | 6.0 | IC50 | 1010.0 | Preclinical |
| CHEMBL4795609 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL222556 | 5.85 | IC50 | 1400.0 | Preclinical |
| CHEMBL4780118 | 5.76 | IC50 | 1740.0 | Preclinical |
| CHEMBL1214872 | 5.09 | IC50 | 8200.0 | Preclinical |
| CHEMBL4797481 | 4.92 | IC50 | 12000.0 | Preclinical |
| CHEMBL1478 | 4.68 | IC50 | 21000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 9 | 5.7 |
| assay format | 1 | 8 | 4.2 |
| tissue-based format | 1 | 1 | 4.7 |