Carnitine O-palmitoyltransferase 1, muscle isoform · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt Q63704. Use UniProt Q63704 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q63704 as the stable identity anchor, then attach disease evidence before program review.
Carnitine O-palmitoyltransferase 1, muscle isoform
Review this target as Carnitine O-palmitoyltransferase 1, muscle isoform, mapped to UniProt Q63704. Sequence length is 772 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Carnitine O-palmitoyltransferase 1, muscle isoform as ChEMBL target CHEMBL3216, mapped to UniProt Q63704. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Carnitine O-palmitoyltransferase 1, muscle isoform |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q63704 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Carnitine O-palmitoyltransferase 1, muscle isoform |
| UniProt Accession | Q63704 |
| Component Type | Protein |
| Sequence Length | 772 aa |
Carnitine O-palmitoyltransferase 1, muscle isoform
Review this target as Carnitine O-palmitoyltransferase 1, muscle isoform, mapped to UniProt Q63704. Sequence length is 772 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2216778 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL2216792 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL2216779 | 7.26 | IC50 | 55.0 | Preclinical |
| CHEMBL2216774 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL2216776 | 6.82 | IC50 | 150.0 | Preclinical |
| CHEMBL2216777 | 6.75 | IC50 | 180.0 | Preclinical |
| CHEMBL1234355 | 5.92 | IC50 | 1200.0 | Preclinical |
| CHEMBL203266 | 5.89 | IC50 | 1300.0 | Clinical |
| CHEMBL1231506 | 5.84 | IC50 | 1450.0 | Clinical |
| CHEMBL80493 | 5.64 | IC50 | 2300.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 9 | 28 | 5.4 |
| mitochondrion format | 5 | 8 | 4.8 |
| assay format | 1 | 1 | 7.4 |
| tissue-based format | 1 | 1 | 5.9 |