Beta-glucuronidase · SINGLE PROTEIN · Escherichia coli (strain K12)
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As of 2026-09-14Protein identity stays anchored to UniProt P05804. Use UniProt P05804 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P05804 as the stable identity anchor, then attach disease evidence before program review.
Beta-glucuronidase
Review this target as Beta-glucuronidase, mapped to UniProt P05804. Sequence length is 603 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-glucuronidase as ChEMBL target CHEMBL3217380, mapped to UniProt P05804. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Beta-glucuronidase is the right protein anchor across sources, using UniProt P05804 as the stable mapping.
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| Preferred Name | Beta-glucuronidase |
| Target Type | SINGLE PROTEIN |
| Organism | Escherichia coli (strain K12) |
| UniProt | P05804 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-glucuronidase |
| UniProt Accession | P05804 |
| Component Type | Protein |
| Sequence Length | 603 aa |
Beta-glucuronidase
Review this target as Beta-glucuronidase, mapped to UniProt P05804. Sequence length is 603 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4589187 | 7.92 | Ki | 12.0 | Preclinical |
| CHEMBL3903683 | 7.75 | EC50 | 18.0 | Preclinical |
| CHEMBL4641364 | 7.55 | EC50 | 28.0 | Preclinical |
| CHEMBL4638468 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL4636276 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL4451253 | 7.13 | Ki | 73.7 | Preclinical |
| CHEMBL4642130 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL1232598 | 6.63 | Ki | 232.0 | Preclinical |
| CHEMBL5410696 | 6.62 | IC50 | 240.0 | Preclinical |
| CHEMBL4643758 | 6.4 | IC50 | 400.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 26 | 64 | 5.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 0 | — |