Transcription initiation factor TFIID subunit 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P21675. Use UniProt P21675 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P21675 as the stable identity anchor, then attach disease evidence before program review.
Transcription initiation factor TFIID subunit 1
Review this target as Transcription initiation factor TFIID subunit 1, mapped to UniProt P21675. Sequence length is 1893 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Transcription initiation factor TFIID subunit 1 as ChEMBL target CHEMBL3217390, mapped to UniProt P21675. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Transcription initiation factor TFIID subunit 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P21675 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Transcription initiation factor TFIID subunit 1 |
| UniProt Accession | P21675 |
| Component Type | Protein |
| Sequence Length | 1893 aa |
Transcription initiation factor TFIID subunit 1
Review this target as Transcription initiation factor TFIID subunit 1, mapped to UniProt P21675. Sequence length is 1893 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4868363 | 9.7 | Ki | 0.1995 | Preclinical |
| CHEMBL4850335 | 9.4 | Ki | 0.3981 | Preclinical |
| CHEMBL4864027 | 9.1 | Ki | 0.7943 | Preclinical |
| CHEMBL4873236 | 9.0 | Ki | 1.0 | Preclinical |
| CHEMBL4854161 | 8.9 | Ki | 1.259 | Preclinical |
| CHEMBL4062266 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL4072812 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL4086958 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL4440829 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL4091912 | 8.22 | IC50 | 6.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 77 | 80 | 6.3 |
| assay format | 44 | 75 | 7.0 |
| cell-based format | 14 | 27 | 5.6 |
| subcellular format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |