Cathepsin B · SINGLE PROTEIN · Capra hircus
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As of 2026-09-14Protein identity stays anchored to UniProt H9B8T9. Use UniProt H9B8T9 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt H9B8T9 as the stable identity anchor, then attach disease evidence before program review.
Cathepsin B
Review this target as Cathepsin B, mapped to UniProt H9B8T9. Sequence length is 335 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cathepsin B as ChEMBL target CHEMBL3232689, mapped to UniProt H9B8T9. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cathepsin B |
| Target Type | SINGLE PROTEIN |
| Organism | Capra hircus |
| UniProt | H9B8T9 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cathepsin B |
| UniProt Accession | H9B8T9 |
| Component Type | Protein |
| Sequence Length | 335 aa |
Cathepsin B
Review this target as Cathepsin B, mapped to UniProt H9B8T9. Sequence length is 335 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL191881 | 10.7 | Ki | 0.02 | Preclinical |
| CHEMBL3309619 | 7.38 | Ki | 42.0 | Preclinical |
| CHEMBL3309796 | 7.28 | Ki | 53.0 | Preclinical |
| CHEMBL3309801 | 6.88 | Ki | 131.0 | Preclinical |
| CHEMBL3309619 | 6.35 | IC50 | 450.0 | Preclinical |
| CHEMBL3309796 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL1588015 | 6.19 | Ki | 640.0 | Preclinical |
| CHEMBL3309801 | 6.13 | IC50 | 740.0 | Preclinical |
| CHEMBL339003 | 6.06 | Ki | 870.0 | Preclinical |
| CHEMBL3238003 | 6.02 | Ki | 950.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 15 | 45 | 5.5 |
| single protein format | 2 | 0 | — |