Cytochrome P450 11B2, mitochondrial · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P30099. Use UniProt P30099 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P30099 as the stable identity anchor, then attach disease evidence before program review.
Cytochrome P450 11B2, mitochondrial
Review this target as Cytochrome P450 11B2, mitochondrial, mapped to UniProt P30099. Sequence length is 510 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cytochrome P450 11B2, mitochondrial as ChEMBL target CHEMBL3237, mapped to UniProt P30099. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cytochrome P450 11B2, mitochondrial |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P30099 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cytochrome P450 11B2, mitochondrial |
| UniProt Accession | P30099 |
| Component Type | Protein |
| Sequence Length | 510 aa |
Cytochrome P450 11B2, mitochondrial
Review this target as Cytochrome P450 11B2, mitochondrial, mapped to UniProt P30099. Sequence length is 510 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3099704 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4080420 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL4067000 | 8.66 | IC50 | 2.2 | Preclinical |
| CHEMBL4098297 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL3099696 | 7.62 | IC50 | 24.0 | Preclinical |
| CHEMBL4080256 | 7.48 | IC50 | 33.0 | Preclinical |
| CHEMBL4071689 | 7.11 | IC50 | 77.0 | Preclinical |
| CHEMBL3099695 | 6.96 | IC50 | 111.0 | Approved |
| CHEMBL287677 | 6.93 | IC50 | 118.0 | Clinical |
| CHEMBL4099824 | 6.52 | IC50 | 300.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 9 | 7.8 |
| single protein format | 4 | 7 | 5.2 |
| assay format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 6 | 5.0 |
| tissue-based format | 4 | 2 | — |