Cyclic AMP-dependent transcription factor ATF-1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P18846. Use UniProt P18846 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P18846 as the stable identity anchor, then attach disease evidence before program review.
Cyclic AMP-dependent transcription factor ATF-1
Review this target as Cyclic AMP-dependent transcription factor ATF-1, mapped to UniProt P18846. Sequence length is 271 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cyclic AMP-dependent transcription factor ATF-1 as ChEMBL target CHEMBL3255, mapped to UniProt P18846. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Cyclic AMP-dependent transcription factor ATF-1 is the right protein anchor across sources, using UniProt P18846 as the stable mapping.
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| Preferred Name | Cyclic AMP-dependent transcription factor ATF-1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P18846 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cyclic AMP-dependent transcription factor ATF-1 |
| UniProt Accession | P18846 |
| Component Type | Protein |
| Sequence Length | 271 aa |
Cyclic AMP-dependent transcription factor ATF-1
Review this target as Cyclic AMP-dependent transcription factor ATF-1, mapped to UniProt P18846. Sequence length is 271 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL336546 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL131636 | 6.92 | IC50 | 120.0 | Preclinical |
| CHEMBL134490 | 6.82 | IC50 | 150.0 | Preclinical |
| CHEMBL135133 | 6.31 | IC50 | 490.0 | Preclinical |
| CHEMBL334485 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL336099 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL423153 | 6.18 | IC50 | 660.0 | Preclinical |
| CHEMBL134603 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL133940 | 5.92 | IC50 | 1200.0 | Preclinical |
| CHEMBL337482 | 5.92 | IC50 | 1200.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 18 | 6.0 |