G-protein coupled receptor 183 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q3U6B2. Use UniProt Q3U6B2 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q3U6B2 as the stable identity anchor, then attach disease evidence before program review.
G-protein coupled receptor 183
Review this target as G-protein coupled receptor 183, mapped to UniProt Q3U6B2. Sequence length is 357 aa.
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This review treats G-protein coupled receptor 183 as ChEMBL target CHEMBL3259471, mapped to UniProt Q3U6B2. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | G-protein coupled receptor 183 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q3U6B2 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | G-protein coupled receptor 183 |
| UniProt Accession | Q3U6B2 |
| Component Type | Protein |
| Sequence Length | 357 aa |
G-protein coupled receptor 183
Review this target as G-protein coupled receptor 183, mapped to UniProt Q3U6B2. Sequence length is 357 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4788348 | 9.15 | EC50 | 0.702 | Preclinical |
| CHEMBL4779254 | 8.79 | EC50 | 1.64 | Preclinical |
| CHEMBL3262895 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL3262896 | 7.86 | IC50 | 13.8 | Preclinical |
| CHEMBL4757291 | 7.84 | EC50 | 14.4 | Preclinical |
| CHEMBL3262890 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL3262889 | 7.7 | IC50 | 19.95 | Preclinical |
| CHEMBL3262892 | 7.68 | IC50 | 20.89 | Preclinical |
| CHEMBL3262894 | 7.64 | IC50 | 22.91 | Preclinical |
| CHEMBL3262879 | 7.54 | IC50 | 28.84 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 2 | 3 | 8.6 |
| cell-based format | 1 | 22 | 7.2 |